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Image Search Results
Journal: Circulation. Heart failure
Article Title: Differential microRNA-21 and microRNA-221 upregulation in the biventricular failing heart reveals distinct stress responses of right versus left ventricular fibroblasts
doi: 10.1161/CIRCHEARTFAILURE.119.006426
Figure Lengend Snippet: (A)Volcano plot of miRNA expression in RV-HF vs RV-Ctrl. Blue dots, miRNAs that were differentially expressed at P<0.10. Labeled dots, miRNAs that were differentially expressed at a minimum 2-fold change in either direction (n=3 per group). (B)Heat maps, Venn diagram, and summary bar graph of differentially expressed miRNAs. Orange font, differentially expressed in RV-HF vs RV-Ctrl and in LV-HF vs LV-Ctrl but not statistically significantly different in RV-HF vs LV-HF. Blue font, differentially expressed in RV-HF vs RV-Ctrl and in RV-HF vs LV-HF, but not statistically significantly different in LV-HF vs LV-Ctrl. Purple font, differentially expressed across all three comparisons: LV-HF vs LV-Ctrl, RV-HF vs RV-Ctrl, and RV-HF vs LV-HF. *P<0.05 vs respective LV-HF/LV-Ctrl. (C)Quantitative RT-PCR analysis of miR-21 and miR-221 in ventricular tissue, n= 6 per group. *P<0.01 vs respective Ctrl; #P<0.01 vs LV HF. (D)Cyclic overstretch and/or aldosterone induced a marked increase in miR-21 (*P<0.01 vs unstimulated) and (E)miR-221 (*P<0.05 vs unstimulated) only in RV fibroblasts. (F)Inhibition of miR-21/−221 attenuated proliferation in RV but not LV fibroblasts. n= 4 per experimental condition. *P<0.05 vs respective LV, #P<0.05 vs RV without antimir, analyzed by ANOVA on Ranks.
Article Snippet: miRNA microarray data was analyzed for differential
Techniques: Expressing, Labeling, Quantitative RT-PCR, Inhibition
Journal: Journal of Biomedical Discovery and Collaboration
Article Title: The emergence and diffusion of DNA microarray technology
doi: 10.1186/1747-5333-1-11
Figure Lengend Snippet: Organizations Receiving the Most Federal Grants for Research Using Microarrays (1993–2004)
Article Snippet:
Techniques:
Journal: Journal of Biomedical Discovery and Collaboration
Article Title: The emergence and diffusion of DNA microarray technology
doi: 10.1186/1747-5333-1-11
Figure Lengend Snippet: Selected Organizations Frequently Citing Affymetrix Patents
Article Snippet:
Techniques: Microscopy, DNA Hybridization, Sequencing, Amplification, Expressing, Imaging, Quantitation Assay, Gene Expression, Drug discovery, Gene Knockout, Sample Prep, Medications, Software, Biomarker Discovery, High Throughput Screening Assay, Diagnostic Assay
Journal: Journal of Biomedical Discovery and Collaboration
Article Title: The emergence and diffusion of DNA microarray technology
doi: 10.1186/1747-5333-1-11
Figure Lengend Snippet: Federal Funding to Perlegen
Article Snippet:
Techniques: Microarray, Sequencing, Genome Wide